منابع مشابه
CASE STUDY Pulmonary toxicity with mefloquine
Pulmonary toxicity with mefloquine. E. Udry, F. Bailly, M. Dusmet, P. Schnyder, R. Lemoine, J.W. Fitting. #ERS Journals Ltd 2001. ABSTRACT: This report presents a case of acute lung injury developing within hours after administration of mefloquine for a low-level Plasmodium falciparum malaria, which was persistent despite halofantrine therapy. Extensive microbiological investigation remained ne...
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The pharmacokinetic and dynamic interactions among 3 antimalarials, ie quinine, doxycycline and mefloquine was observed in a 26-year-old Thai male patient with falciparum malaria. During the acute episode of the infection, the patient was treated with an intravenous dose of quinine hydrochloride at 600 mg qid, together with an oral dose of doxycycline 100 mg bid. Due to nausea, tinnitus and the...
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Gemcitabine (2’,2’-difluoro-s’-deoxycytidine; Gemzar, Eli Lilly, Indianapolis, IN, USA), a pyrimidine nucleoside analogue similar to cytarabine, inhibits DNA synthesis both by halting DNA replication through the incorporation of its active form into DNA and also by inhibiting ribonucleotide reductase and deoxycytidine monophosphate deaminase [1, 2]. It is administered as a prodrug that becomes ...
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Mefloquine use has been linked to severe gastrointestinal and neuropsychiatric adverse effects, including cognitive disturbances, anxiety, depression, psychosis, and violence. The adverse effects of the drug are thought to result from the secondary consequences of hepatocellular injury; in fact, mefloquine is known to cause a transient, anicteric chemical hepatitis. However, the mechanism of me...
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Gemcitabine is a nucleoside analog that has been increasingly used in the chemotherapy of solide tumors, including breast, pancreas ovary and non small cell lung cancer. It is generally well tolerated and has few side effects. Gemcitabine induced pulmonary complications range from mild dyspnea to death from ARDS. A 57yearold man was treated with six cycles of gemcitabine because of pancreatic c...
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ژورنال
عنوان ژورنال: European Respiratory Journal
سال: 2001
ISSN: 0000-0000,0903-1936
DOI: 10.1183/09031936.01.00208001